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Differential Clinical Significance of Medical Information

Mathematical Expression of It Needed

In English



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Differential Clinical Significance of Medical Information
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  • a. Dedication :
    To Prof. Peter Goldstraw, the gentleman who taught me “the Art” (as Hippocrates referred to it) and Ethics; he has always been so wise and kind a mentor that I can never repay the debt I owe him
    Portrait of Prof. Peter Goldstraw, FRCS
  • b. Synopsis :
    Modern Medicine desperately needs an absolute theoretical (logarithmic or exponential) basis to mathematically quantify the Significance of medical digital information (or data) that are stored in each patient’s digital records, to establish some necessary hierarchy or order in a way ... 

    ... similar to the order achieved by the concept of “Indications” (for different forms of treatment etc.) to the pre-hippocratic chaos of erratic personal arbitrary medical opinions, then heavily biased.

    If a quantification of medical information’s Differential Significance is achieved, then the following dangers can be eliminated:

    crucial, important medical information in small quantity, expressed in fewest bits (e.g. ‘Presence or Absence of spread of a cancer after staging investigations and procedures,’ ‘patient Alive or Dead’), may be hidden in a flooded ocean of large amounts of data (in GBs) much less important,

    deep learning diagnostic algorithms may not become efficient to recognize the sequential hierarchy of significance of heterogenous medical digital data that should be taken into account in order to reach a safe and reasonable final conclusion.—
  • c. Topics discussed in the book :
    • Bioinformatics
    • Medical Informatics
    • Data Mining (medical)
    • Deep Learning (diagnostic algorithms)
    • Diagnoses:
      • Differential Diagnoses
      • Classifications of Diagnoses:
        • ICD-10
        • DRGs (Diagnosis-Related Groups)
      • Diagnostic algorithms (Deep Learning)
    • Decision-Making in Medicine
    • Conflicting Priorities
    • Hierarchy or Priorities of Significance of digital medical data
    • Staging of Cancer
    • C. E. Shannon's Information theory
    • Alan Turing
    • Concept of "Indications" invented by Hippocrates
    • Linear b syllabary: I-JA-TE

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